Over-the-counter weight-loss pills: Do they work?

Over-the-counter weight-loss pills: Do they work?
The temptation to use over-the-counter weight-loss pills to lose weight fast is strong. But are these products safe and effective?
By Mayo Clinic staff

The appeal of losing weight quickly is hard to resist. But do weight-loss pills and products lighten anything but your wallet? And are they a safe option for weight loss? Here's a look at some over-the-counter weight-loss pills and what they will and won't do for you.
Over-the-counter doesn't mean risk-free

A number of weight-loss pills are available at your local drugstore, supermarket or health food store. Even more options are available online. Most haven't been proved effective, and some may be downright dangerous.

Dietary supplements and weight-loss aids aren't subject to the same rigorous standards as are prescription drugs. Thus, they can be sold with limited proof of effectiveness or safety. Once a product is on the market, however, the Food and Drug Administration (FDA) monitors its safety and can take action to ban or recall dangerous products. Indeed, the FDA has banned the sale of supplements containing ephedra and other ephedrine-like ingredients.
Check the facts before you buy

It's important to do your homework if you're thinking about trying over-the-counter weight-loss pills. Read labels and talk with your doctor or pharmacist. Also be sure to check the FDA website for alerts about safety concerns and product recalls.

The table shows common weight-loss pills and what the research shows about their effectiveness and safety.